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mg-25 is a stable (non-radioactive) metallic isotope of Magnesium. It is one of over 250 stable Metallic isotopes produced by American Elements for biological and biomedical labeling, as target materials and other applications.

This isotope can be used to study the absorption and metabolism of magnesium in the body. Hundreds of enzymes require magnesium ions to function.

The chemical bonds of magnesium ions are essential for polyphosphate compounds such as DNA and RNA. In addition, many carbohydrate metabolic processes and photosynthetic pigments are dependent on the magnesium ion.

Symptomatic magnesium deficiency is uncommon in healthy people. However, chronic alcoholism and certain health conditions can reduce dietary intake of magnesium.

Low dietary magnesium intake is common in children, and this may contribute to deficiency. Moreover, some medications can lead to magnesium deficiency.

Isotopic tracer studies are a potentially useful tool to assess Mg absorption and metabolism in infants. Fractional absorption, isotope retention, endogenous fecal Mg losses and apparent Mg exchangeable pool size were assessed in three full-term human infants administered 25Mg orally as an in vivo tracer over 24 h.

High precision direct analysis of Mg isotope ratio by ion chromatography/multicollector-ICPMS using wet and dry plasma conditions was performed. The results showed that the magnesium isotopes are rapidly absorbed from the intestinal tract, accompanied by isotopic retention and endogenous fecal Mg loss.

It is best to take this product at least 4 hours before or 4-6 hours after taking oral bisphosphonates, such as alendronate (Fosamax(r)). This will help prevent the decrease in magnesium absorption and metabolism that may occur when these drugs are taken together.

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